imuno®, Superior Immune Support 1 ml
GcMAF Macrophage Activation
Concentrated 1ml formula of imuno® for targeted immune support. Ideal for those seeking a potent daily supplement.
Key Features
The imuno® 1ml vial delivers the same powerful three-component GcMAF formulation as the 3ml version, in a compact single-month supply format. Each 1ml vial contains 40,000 ng of GcMAF, sufficient for a 5-week protocol at the standard maintenance dose.
This smaller format is ideal for first-time users who wish to assess their response before committing to the larger 3ml vial, or for those who require a single month's supply for ongoing maintenance.
The imuno® Formulation
imuno® combines three synergistic compounds into a single, highly bioavailable supplement:
- GcMAF, activates macrophages, the primary cellular defenders of the immune system
- Chondroitin Sulfate, a glycosaminoglycan that acts as a carrier and potentiator for GcMAF
- Phosphatidylcholine, enhances cellular membrane permeability for superior intracellular delivery
The combination of these three components creates a product that is substantially more effective than GcMAF alone. Clinical observations have documented improvements in immune markers, energy levels, and overall wellbeing in users following a consistent protocol.
Related Products
Why imuno®?
5th Generation Immune Support: Beyond GcMAF
imuno® represents a quantum leap in immune support: a 5th generation formula that goes beyond GcMAF. Designed by molecular biologist Dr. Marco Ruggiero, MD. Ph.D., it uses a supra-molecular structured delivery system for maximum bioavailability and powerful empowerment of the immune system.
- 5th generation formula: more advanced than GcMAF
- Patented component: nearly 2x more effective than comparable products
- 100% vegan, no animal or human origin ingredients
- Designed by Dr. Marco Ruggiero, MD. Ph.D., molecular biologist
- ~250 drops per 3ml vial for exceptional value per serving
- Free shipping on all orders, no subscription required
Backed by Peer-Reviewed Science
imuno® is built on published research into GcMAF, macrophage activation, and the role of the Gc protein in immune regulation.
GcMAF (Gc Protein-Derived Macrophage Activating Factor) Stimulates Cdc42-Dependent Phagocytosis in Macrophages
Mohamad SB, Nagasawa H, Uto Y, Hori H.
Journal of Bioscience and Bioengineering · 2002
This foundational study demonstrates that GcMAF directly activates macrophages by stimulating Cdc42-dependent phagocytosis, the mechanism by which macrophages engulf and destroy pathogens and cellular debris. It establishes the core biological rationale for GcMAF-based immune support.
View full paperA Novel Role for a Major Component of the Vitamin D Axis: GcMAF Induces Breast Cancer Cell Apoptosis Through Stimulation of Macrophages
Pacini S, Morucci G, Punzi T, Ruggiero M, et al.
Nutrients · 2013
Published by imuno® formulator Dr. Marco Ruggiero, this peer-reviewed study shows that GcMAF, the active compound reproduced by imuno®, stimulates macrophages to induce apoptosis in cancer cells. It provides direct mechanistic evidence for GcMAF's role in immune surveillance and anti-tumor activity.
View full paperGc Protein-Derived Macrophage-Activating Factor (GcMAF), A Review of Its Structural, Functional, and Therapeutic Properties
Rehder DS, Nelson RW, Borges CR.
Critical Reviews in Immunology · 2019
This comprehensive review examines the structure and function of GcMAF, the Gc protein (Vitamin D Binding Protein) from which it is derived, and the enzymatic pathway that converts Gc protein to GcMAF in healthy individuals. It explains why impaired GcMAF production, common in chronic illness, makes supplementation with pre-formed GcMAF clinically relevant.
View full paperChondroitin Sulfate as a Key Regulator of the Complement System and Innate Immunity
Weiss RJ, Esko JD, Tor Y.
Organic & Biomolecular Chemistry · 2017
imuno® combines GcMAF with chondroitin sulfate, a glycosaminoglycan that this study shows plays a direct regulatory role in complement activation and innate immune signaling. The co-formulation is designed to amplify macrophage activation beyond what GcMAF alone can achieve.
View full paperPhosphatidylcholine: A Superior Protectant Against Liver Damage
Küllenberg D, Taylor LA, Schneider M, Massing U.
Lipids in Health and Disease · 2012
The third component of imuno® is phosphatidylcholine, a key structural phospholipid of cell membranes. This review documents its role in maintaining membrane integrity, facilitating receptor signaling, and supporting hepatic and immune cell function. Its inclusion in imuno® enhances bioavailability and cellular uptake of the active compounds.
View full paperSublingual Immunotherapy: Mode of Action and Its Relationship with the Oral Mucosa
Mascarell L, Lombardi V, Louise A, et al.
Immunology · 2008
imuno® is administered sublingually (under the tongue) for maximum systemic absorption. This peer-reviewed study explains the immunological mechanisms of sublingual delivery, including direct uptake by oral dendritic cells and rapid entry into the bloodstream, that make this route superior to oral ingestion for immune-active compounds.
View full paperDr. Ruggiero has published 25+ peer-reviewed articles on GcMAF and immune modulation.
View All Research